The Eagles' forward line has given opposition coaches headaches all season, with Josh Kennedy (194cm), Jack Darling (191cm) and Quinten Lynch (192cm) the primary targets and ruckmen Dean Cox (203cm) and Nic Naitanui (201cm) often floating forward.
Despite missing defensive pillars Daniel Merrett (back) and Joel Patfull (hand) for the finish of the season, Staker believes the Lions can keep West Coast's big men quiet.
He said Saturday night's 18-point loss against Collingwood was a good rehearsal.
"We matched up against a really strong forward line last weekend and held our own I thought," he said.
" It was impressive to see.
"Matt Maguire stepped up, Josh Drummond has had an interrupted year but he did a great job and provided a lot for us, and guys like Pearce Hanley provide us with run, so if we can do that, they're the little keys to having a good night.
"Looking at it on paper we match up pretty well with them. If we get that right and get that competitiveness again and bring the right attitude that'll take us a long way (towards winning)."
Maguire and Irishman Niall McKeever, who had the arduous task of matching Magpie giant Travis Cloke in just his eighth AFL match, hold down the two key defensive positions.
Staker himself has switched between back and forward since returning from an ACL injury in round 17, and at 196cm may have to help the back six against the Eagles.
It will be the third time the 27-year-old has played against West Coast since switching camps at the end of 2009 following 110 matches in blue and gold.
"It's always exciting playing your old team because I've got so many mates there," he said.
"I suppose the first time you play against your old team, round one last year, it was an extra special feeling, whereas now it's just another team and another game of football and that's the way you've got to look at it.
"They're a good team, they're playing some good football and it's another good challenge for us as a whole team to step up to the plate again on Saturday night."
Staker said the Lions showed great competitive spirit against Collingwood but needed to turn that into wins.
"A game like that against a top of the ladder team … we weren't put off by it or didn't go into our shell, we enjoyed the environment we were in at the MCG on a Saturday night and embraced it and played some good football," he said.
"Coming away with a loss is not good enough though. We don't accept honourable losses."
Michael Whiting covers Brisbane Lions news for afl.com.au. Follow him on Twitter: @mike_whiting
