Andrews missed four matches after suffering
Lions coach Chris Fagan confirmed on Thursday both Andrews and Luke Hodge, who has missed two matches with a calf injury, would be available to play the Cats.
Fagan said Andrews had been doing contested work all week to prove his fitness.
"We did some match practice this morning where he had to fly back with the flight and go for his marks and he didn't seem to be any different to the normal Harris Andrews," Fagan said.
"But we'll wait and see, he's only human.
"Maybe the game situation is a little bit different, hopefully not, but he's certainly ready to go."
Fagan said Andrews would resume his customary role as a key defender.
The 21-year-old was in All Australian form and arguably leading the club's best and fairest prior to his setback, but Fagan said his main concern was the health of his vice-captain.
"In a funny sort of way they all feel like your sons when you're the coach, you're always concerned for their health and wellbeing.
"Each week we ask them to go out and do things that most human beings wouldn't consider doing.
"He's a very courageous player. I'm very pleased he's made a full recovery."