Brennan has recovered from a quad strain and returns for his first match of the 2009 season while Charman has been included in the team after gaining valuable match practice with the Lions Reserves last week.
The pair replaces Matthew Leuenberger – who underwent knee surgery earlier this week – and Albert Proud who has been omitted from the side that defeated Sydney by 33 points last Saturday night.
The inclusion of both Brennan and Charman adds valuable experience to the Lions team who are searching for their third win for the season.
The full Lions team is:
B: Ashley McGrath (9), Daniel Merrett (21), Joel Patfull (24)
HB: Luke Power (6), Joel Macdonald (26), Josh Drummond (39)
C: Bradd Dalziell (34), Simon Black (20), Daniel Rich (10)
HF: Michael Rischitelli (35), Jonathan Brown (16), Justin Sherman (11)
F: Tim Notting (8), Daniel Bradshaw (36), Mitch Clark (1)
Foll: Jamie Charman (19), Travis Johnstone (4), Jed Adcock (7)
Int: Jared Brennan (17), Cheynee Stiller (32), Jason Roe (29), Troy Selwood (28)
Emerg: James Polkinghorne (31), Tom Collier (22), Albert Proud (2)
IN: Brennan, Charman
OUT: Leuenberger (knee), Proud (omit)